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This stinks:
New research finds sense of smell and pneumonia linked

EAST LANSING, Mich., USA (May 11, 2021) — An acute loss of smell is one of the most common symptoms of COVID-19, but for two decades it has been linked to other maladies among them Parkinson’s disease and dementia. Now, a poor sense of smell may signify a higher risk of pneumonia in older adults, says a team of Michigan State University researchers.

„About a quarter of adults 65 years or older have a poor sense of smell,“ said Honglei Chen, a professor in the Department of Epidemiology and Biostatistics within MSU’s College of Human Medicine. „Unlike vision or hearing impairment, this sensory deficit has been largely neglected; more than two-thirds of people with a poor sense of smell do not know they have it.“

In a first-of-its-kind study, Chen and his team found a possible link between poor sense of smell and a higher risk of pneumonia hospitalization. They analyzed 13 years of health data from 2,494 older adults, ages 71-82, from metropolitan areas of Pittsburgh, Pennsylvania, and Memphis, Tennessee. This study aimed to examine whether a poor sense of smell in older adults is associated with a higher future risk of developing pneumonia.

Chen’s research was recently published in the journal The Lancet Healthy Longevity. The participants were given a Brief Smell Identification Test, or B-SIT, using common smells such as lemons and gasoline to determine if their sense of smell was good, moderate or poor. Then, the participants were monitored for the next 13 years using clinical exams and follow-up phone calls to identify hospitalization due to pneumonia.

The researchers found that compared with participants who had a good sense of smell, participants with a poor sense of smell were about 50% more likely to be hospitalized with pneumonia at any time point during the 13-year follow-up. Among participants (with a poor sense of smell) who never had had pneumonia before, the risk of having the first-ever pneumonia was about 40% higher.

„To our knowledge, this study provides the first epidemiological evidence that poor olfaction (sense of smell) is associated with a long-term higher risk of pneumonia in older adults,“ said Yaqun Yuan, a postdoctoral fellow in Chen’s research group.

This study provides novel evidence that a poor sense of smell may have broader health implications beyond its connections to Parkinson’s disease and dementia.

„This is just an example how little we know about this common sensory deficit,“ Chen said. „Either as a risk factor or as a marker, poor sense of smell in older adults may herald multiple chronic diseases beyond what we have known about. We need to think out of the box.“

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Michigan State University has been working to advance the common good in uncommon ways for more than 165 years. One of the top research universities in the world, MSU focuses its vast resources on creating solutions to some of the world’s most pressing challenges, while providing life-changing opportunities to a diverse and inclusive academic community through more than 200 programs of study in 17 degree-granting colleges.

For MSU news on the Web, go to MSUToday. Follow MSU News on Twitter at twitter.com/MSUnews.

Michigan State University, 11.05.2021 (tB).